For general education only. This information does not diagnose a condition or replace medical advice. Your provider will determine which evaluation or treatment is appropriate for you.
How to read this table
This table compares categories of options. It does not rank them, declare a winner, or suggest that any option is right for you. Your provider determines suitability after reviewing your health history, current medicines, labs, and goals. Nothing here replaces that evaluation.
None of these is a treatment for a diagnosed condition in the way a prescription for diabetes or high blood pressure is. The useful question is what specific benefit is expected and what evidence supports it.
Approval, off label use, and compounding
FDA approval applies to a specific product, formulation, indication, and population. Off label use means an approved medicine is prescribed outside its approved labeling. A compounded preparation is not FDA approved and has not undergone the same premarket review for safety, effectiveness, and quality.
These listings are marketed as supplements or compounded preparations. A compounded preparation is not FDA approved, and no product here is approved to slow, reverse, or treat aging. An ingredient name alone does not establish approval. Ask for the exact product name, formulation, and current labeling of the medicine offered to you, and whether that use is approved, off label, or compounded.
What a useful conversation covers
A biological role is not a proven benefit. That a nutrient is involved in energy production or antioxidant defenses does not establish that taking more of it improves energy, appearance, or lifespan.
Ask what would count as a meaningful benefit for you, how it would be measured, what it costs, and when to stop. Established foundations such as movement, sleep, nutrition, preventive care, and not smoking remain the better supported starting point.
Side by side
Considerations worth bringing to your provider. This is not a ranking, and it does not mean any option is right for you.
NAD+ oral
Product details- What it is
- A supplement aimed at a coenzyme involved in cellular energy that declines with age.
- How it is used
- Taken daily as directed.
- Approval and labeling
- Sold as a supplement. Not approved to treat, prevent, or reverse aging.
- What the evidence supports
- Human evidence for energy, focus, or aging outcomes from an oral supplement is limited.
- Common considerations
- Mild flushing or digestive upset may occur.
- Often not appropriate when
- You are pregnant or breastfeeding, or a documented condition or deficiency needs proper treatment instead.
- Cost and access
- Pricing is shared after your evaluation. Ask what your plan includes, such as consultations, medication, labs, and follow up, and what happens if your plan changes.
Glutathione oral
Product details- What it is
- A daily supplement aimed at the body antioxidant defenses.
- How it is used
- Taken daily as directed.
- Approval and labeling
- Sold as a supplement. Not approved to treat, prevent, or reverse aging.
- What the evidence supports
- Oral absorption and meaningful effects on antioxidant status in healthy people are not well established.
- Common considerations
- Mild digestive upset may occur.
- Often not appropriate when
- You are pregnant or breastfeeding, or a documented condition or deficiency needs proper treatment instead.
- Cost and access
- Pricing is shared after your evaluation. Ask what your plan includes, such as consultations, medication, labs, and follow up, and what happens if your plan changes.
Glutathione injection
Product details- What it is
- An injected form of the same antioxidant, delivered directly.
- How it is used
- Given on a schedule your provider sets.
- Approval and labeling
- Often a compounded preparation, which is not FDA approved. Ask about the source and quality checks.
- What the evidence supports
- Evidence for skin clarity, detoxification, or energy benefits in healthy people is limited.
- Common considerations
- Injection site reactions may occur.
- Often not appropriate when
- You are pregnant or breastfeeding, or a documented condition or deficiency needs proper treatment instead.
- Cost and access
- Pricing is shared after your evaluation. Ask what your plan includes, such as consultations, medication, labs, and follow up, and what happens if your plan changes.
MIC B12
Product details- What it is
- An injected blend of methionine, inositol, and choline with vitamin B12, described as a lipotropic combination.
- How it is used
- Given on a regular schedule your provider sets.
- Approval and labeling
- Often a compounded preparation, which is not FDA approved. Ask about the source and quality checks.
- What the evidence supports
- Evidence that this injection supports weight loss or energy beyond correcting a deficiency is lacking.
- Common considerations
- Injection site soreness may occur. A B12 injection only helps if a deficiency is present.
- Often not appropriate when
- You are pregnant or breastfeeding, or a documented condition or deficiency needs proper treatment instead.
- Cost and access
- Pricing is shared after your evaluation. Ask what your plan includes, such as consultations, medication, labs, and follow up, and what happens if your plan changes.
Questions to bring
- What specific benefit do you expect from this, and what human evidence supports it?
- Is this a supplement or a compounded preparation, and what quality checks apply?
- Am I being treated for a documented deficiency or condition?
- How would we measure whether it is worth continuing?